Overview
A low-noise multi-channel acquisition board designed for cortical research applications requiring simultaneous recording from large electrode arrays.
- 32 channels of low-noise amplification with programmable bandwidth and gain.
- Input-referred noise performance below 5 µV RMS over full recording bandwidth.
- Shielding and layout isolation preventing digital switching noise from coupling into the analogue stage.
- High-resolution ADC with sampling rates optimized to capture sub-millisecond spike waveforms.
- Continuous high-bandwidth USB 3.0 data streaming to host PC acquisition systems.
- Companion Python library for real-time data streaming, configuration, and spike detection.
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Challenge
Routing a 128-channel cortical probe connection on a flexible substrate with trace width/spacing constraints under 50 µm.
Solution
Designed a high-density interconnect (HDI) flex PCB using microvias, ENIG surface finish, and polyimide substrate materials.
Outcome
Delivered biocompatible probe interfaces with high signal integrity and mechanical reliability in pre-clinical studies.